Adrian Liston
Research Summary
The Liston laboratory works on regulatory T cells. These are a type of white blood cell that act to suppress the rest of the immune response, preventing spontaneous autoimmune disease and acting as a rheostat to control just how active our immune system is. The number of these cells in our blood goes up as we get old, which may contribute to the immune-suppressed state of older persons. We seek to understand these cells, using both patient material and mouse models, so that we can harness their power to fine-tune the immune system for healthy ageing.
Latest Publications
A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice. Med (New York, N.Y.), 1, 1, 16 Dec 2020 PMID: 33521747 |
|
Author Correction: The cellular composition of the human immune system is shaped by age and cohabitation. Nature immunology, 1, 1, 25 Nov 2020 PMID: 33239822 |
|
Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19. Clinical & translational immunology, 9, 11, 2020 PMID: 33209300 |