Life Sciences Research for Lifelong Health

The Babraham Institute undertakes world-leading research into understanding the biology of how our bodies work, including what changes as we age and during disease. Our research is split into four programmes: Epigenetics, Signalling, Lymphocyte Signalling and Nuclear Dynamics, supported by strategic programme grants from the Biotechnology and Biological Sciences Research Council (BBSRC) and additional funding from research councils, the EU and charities.

We maximise the impact of our research through Knowledge Exchange, Commercialisation and Public Engagement activities. We do this by collaborating with other academics, policy makers, charities, schools, the general public and industry, including companies on the Babraham Research Campus. Commercialisation is achieved in collaboration with the Institute’s wholly-owned trading arm, Babraham Institute Enterprise Limited.


13/09/2017

A hair-trigger for cells fighting infection

The Turner lab reveal how immune cells get creative with their genes, without causing lasting harm

The protein Tia1 stops cells in the immune system from going…


05/09/2017

Older wombs linked to complications in pregnant mice

The Hemberger Lab examine placenta formation in ageing mice

Increased risk of pregnancy complications for older mothers…


22/08/2017

Over 6,700 computational models of cancer now available online

The models are shared on the BioModels platform managed by the Le Novère lab and EMBL-EBI

Patient-derived models using data from real cancer patients…

Access our Science Services

Imaging
Flow Cytometry
Sequencing
Lipidomics
Gene Targeting
Biological Support Unit
Mass Spectrometry
Biological Chemistry
Bioinformatics
Imaging

The Imaging Facility provides supported access to advanced fluorescence imaging technologies and image analysis solutions.

Flow Cytometry
The Babraham Institute Flow Cytometry Core Facility offers high quality service and state-of-the-art instrumentation to members of Babraham Institute and external users.
Sequencing
The Facility plays a crucial role in all the Institute’s research programmes and is also available to external users on a fee-for-service basis
Lipidomics
We have established methods to analyse neutral lipids, phospholipids and sphingolipids using a Shimadzu IT-TOF mass spectrometer coupled to a Prominence HPLC system
Gene Targeting
Providing a complete service to generate genetically altered mouse strains for Babraham Institute research groups and external companies
Biological Support Unit
Our state-of-the-art Biological Support Unit provides housing and care for pathogen-free rodents used in the academic research programmes and by private companies
Mass Spectrometry
The Mass Spectrometry Facility is housed in a purpose-built laboratory in a new building in the centre of the campus
Biological Chemistry
Biological chemistry is the interface between chemistry and biology, requiring both synthetic organic chemistry skills and a knowledge of biochemistry
Bioinformatics
The bioinformatics group provides an interface between the computational infrastructure of the insitute and the biology performed within the research groups

21/09/2017

In vivo and in vitro imaging of leukocyte responses during inflammation

Dr Aleksandar Ivetic; Kings College London


28/09/2017

miR-221 promotes precursor B-cell retention in bone marrow by amplifying the Pi3K-signaling pathway

Dr Georg Petkau; German Rheumatism Research Centre, Berlin


06/10/2017

Live cell biochemistry by light

MRC Cancer Unit, University of Cambridge

Dr Alessandro Esposito


14/10/2017

Making your Mark: Exploring Epigenetics at Big Biology Day

Making your Mark: Exploring Epigenetics at Big Biology Day


27/10/2017

STEM Insight Week teacher placements

Apply by 15th September

For teachers who want to get back to the bench!


25/10/2017

Bioscience lite - CRISPR genome editing – technology, applications and implications

CRISPR genome editing

CRISPR genome editing – technology, applications and implications.

 

Key visitor pages

Academia

The following pages may be of particular interest to those in the Academic community:

Media

Members of the media and journalists may wish to visit the following sections for further details about our work:

Public

Members of the public may wish to look at the following pages to find out how the Babraham Institute works with and for society:

Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells.

Díaz-Muñoz MD, Kiselev VY, Novère NL

Nature communications
8 2041-1723:530 (2017)

PMID: 28904350

RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.

Tarling EJ, Clifford BL, Cheng J

The Journal of clinical investigation
1558-8238: (2017)

PMID: 28891815

Significance of stroma in biology of oral squamous cell carcinoma.

Vucicevic Boras V, Fucic A, Virag M

Tumori
2038-2529:0 (2017)

PMID: 28885677

Decidualisation and placentation defects are a major cause of age-related reproductive decline.

Woods L, Perez-Garcia V, Kieckbusch J

Nature communications
8 2041-1723:352 (2017)

PMID: 28874785