The Babraham Institute undertakes world-leading research into understanding the biology of how our bodies work, including what changes as we age and during disease. Our research is split into three programmes: Epigenetics, Signalling, and Lymphocyte Signalling, supported by strategic programme grants from the Biotechnology and Biological Sciences Research Council (BBSRC) and additional funding from research councils, the EU and charities.

We maximise the impact of our research through Knowledge Exchange, Commercialisation and Public Engagement activities. We do this by collaborating with other academics, policy makers, charities, schools, the general public and industry, including companies on the Babraham Research Campus. Commercialisation is achieved in collaboration with the Institute’s wholly-owned trading arm, Babraham Institute Enterprise Limited.



Melanie Eckersley-Maslin receives award for stem cell research

2020 winner of a Metcalf Prize

Australian Prize recognises leadership in stem cell research


Institute’s response to new national lockdown

Institute’s coronavirus response plan and current status explained

Phased response permits essential and prioritised research


Exploring the effects of age on the immune response to Oxford’s COVID-19 vaccine

Applying Institute expertise in immunology and ageing

Young and aged mice used to chart immune response


Single-cell technique could provide ‘egg health’ indicators

Do genomic changes contribute to poor egg quality?

Learning more about the effects of age on reproductive success

Access our Science Facilities

Biological Support Unit
Biological Chemistry
Flow Cytometry
Mass Spectrometry
Gene Targeting

Providing comprehensive tools and analysis for life sciences Key services Bioinformatics Analysis Consultancy Statistics Training Software Infrastructu


The Imaging Facility provides a high quality microscopy and image analysis service, enabling scientists to use advanced imaging methods in their research. We provide trai


Next Generation Sequencing technology has revolutionised post-genomics studies of gene expression, genetic regulation and nuclear dynamics. The Sequencing Facility provid

Biological Support Unit

Our state-of-the-art Biological Support Unit provides housing and care for pathogen-free rodents. It supports research across the Institute as well as providing services


The Lipidomics Facility undertakes the detection and identification of lipids, with a focus on providing biological meaning to these generated lipid profiles through bios

Biological Chemistry

To provide a research interface between chemistry and biology to solve biological questions. Key services Chemical synthesis (bio-active molecules, fluorescent or i

Flow Cytometry

The Babraham Institute Flow Cytometry Core Facility offers high quality service and state-of-the-art instrumentation to members of Babraham Institute and external users.

Mass Spectrometry

The primary role of the Facility is to apply state of the art techniques in mass spectrometry to address important biological questions, within the remit of the Institute

Gene Targeting

To deliver gene targeting capabilities including the production of transgenic mouse models. Key services Generation of mouse models; ranging from single nucleoti


Roles of TCR signal strength and duration in driving T cell development, differentiation and function

Dr David Bending

Institute of Immunology and Immunotherapy, University of Birmingham


Symmetry breaking and self-organization in intestinal organoids

Prof. Prisca Liberali

SNSF Professor and Research Group Leader, Friedrich Miescher Institute for Biomedical Research (FMI)


UK Autophagy Network seminar - “Molecular Mechanisms of Selective Autophagy”

Prof. Sascha Martens

Max Perutz Labs, University of Vienna


Gender differences in question-asking at academic seminars

Dr Gillian Sandstrom

Senior Lecturer, University of Essex

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Key visitor pages

Members of the public may wish to look at the following pages to find out how the Babraham Institute works with and for society:

The following pages may be of particular interest to those in the Academic community:

Members of the media and journalists may wish to visit the following sections for further details about our work:

Cell-cell coupling and DNA methylation abnormal phenotypes in the after-hours mice.

Tinarelli F, Ivanova E, Colombi I,

Epigenetics & chromatin
14 1: 06 Jan 2021

PMID: 33407878

A RAC-GEF network critical for early intestinal tumourigenesis.

Pickering KA, Gilroy K, Cassidy JW,

Nature communications
12 1: 04 01 2021

PMID: 33397922

Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ.

Webb LMC, Fra-Bido S, Innocentin S,

Aging cell
1 1: 02 Jan 2021

PMID: 33387451

Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington's disease.

Alcalá-Vida R, Garcia-Forn M, Castany-Pladevall C,

EMBO molecular medicine
1 1: 28 Dec 2020

PMID: 33369245