Life Sciences Research for Lifelong Health

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Research Groups

The Babraham Institute’s research focuses on understanding fundamental biology and its role in healthy ageing and disease. Our research groups form three strategic research programmes; epigenetics, signalling and lymphocyte signalling. You can discover more about all our research groups below.

In addition, we have a number of affiliated research groups and the Institute operates several scientific facilities. Each facility employs a specialist team with skills and expertise in key cutting-edge research techniques.
 


Geoff Butcher

Lymphocyte Signalling
Maintaining the immune cell population through lymphocyte homeostasis and the role of GIMAP proteins in this process
 

Olivia Casanueva

Epigenetics
Mechanisms linked to stress and ageing in C. elegans worms and how they vary between individuals
 

Simon Cook

Signalling
The role of protein kinases in cellular responses to growth factors, nutrient availability or stress and damage
 

Anne Corcoran

Lymphocyte Signalling
Understanding the role of chromatin and nuclear organisation in controlling gene expression during the development of the immune system
 

Oliver Florey

Signalling
The role of autophagy and other cellular ‘eating’ processes in normal biology and during ageing or disease
 

Phill Hawkins

Signalling
The molecular mechanisms and physiological significance of signalling networks involving phosphoinositide 3-kinases (PI3Ks)
 

Jon Houseley

Epigenetics
The mechanisms by which cells learn to adapt and thrive in new environments
 

Gavin Kelsey

Epigenetics
The epigenetics of the egg and sperm and their role in carrying information between generations
 

Nicholas Ktistakis

Signalling
How autophagy contributes to health and healthy ageing by eliminating damage and recycling cell components
 

Michelle Linterman

Lymphocyte Signalling
Understanding the changes that occur in T cells with age that contribute to the age-dependent decline in the germinal centre response
 

Adrian Liston

Lymphocyte Signalling
The role of regulatory T cells in controlling and suppressing the immune system and the effect of age on these cells
 

Wolf Reik

Epigenetics
The role of epigenetics in cell identity and factors involved in the process of epigenetic reprogramming

Claudia Ribeiro de Almeida

Lymphocyte Signalling
The molecular mechanisms underlying diversification of antibody genes by B cells in the immune system
 

Sarah Ross

Lymphocyte Signalling
The effect of factors like oxygen levels on gene expression and regulation in T cells of the immune system
 

Rahul Roychoudhuri

Lymphocyte Signalling
How tolerance mechanisms in the immune system help to prevent autoimmunity and allergies, and their use in therapies
 

Peter Rugg-Gunn

Epigenetics
The epigenome in stem cells and development, and how epigenetics changes through the life course
 

Stefan Schoenfelder

Epigenetics
The functional organisation of the genome in three dimensions (Dr Schoenfelder is an independent Career Progression Fellow)
 

Len Stephens

Signalling
The molecular mechanisms and physiological significance of signalling networks involving phosphoinositide 3-kinases (PI3Ks)
 

Martin Turner

Lymphocyte Signalling
Gene expression and the roles of RNAs in the development and function of lymphocytes
 

Michael Wakelam

Signalling
Understanding the essential physiological functions of lipids particularly during healthy ageing
 

Heidi Welch

Signalling
Control of cell shape, movement, gene expression and other factors by Rac-GEF proteins