Life Sciences Research for Lifelong Health

Group Members


Dr Rahul Samant


Latest Publications

Dosage compensation plans: protein aggregation provides additional insurance against aneuploidy.

Samant RS, Masto VB, Frydman J

Genes & development
33 1549-5477:1027-1030 (2019)

PMID: 31371460

Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae.

Samant RS, Frydman J

Methods in enzymology
619 1557-7988:27-45 (2019)

PMID: 30910025

Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control.

Samant RS, Livingston CM, Sontag EM

563 1476-4687:407-411 (2018)

PMID: 30429547

Mechanisms and Functions of Spatial Protein Quality Control.

Sontag EM, Samant RS, Frydman J

Annual review of biochemistry
86 1545-4509:97-122 (2017)

PMID: 28489421

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.

Dale T, Clarke PA, Esdar C

Nature chemical biology
11 1552-4469:973-980 (2015)

PMID: 26502155

E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells.

Samant RS, Clarke PA, Workman P

Proceedings of the National Academy of Sciences of the United States of America
111 1091-6490:6834-9 (2014)

PMID: 24760825

ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.

Polier S, Samant RS, Clarke PA

Nature chemical biology
9 1552-4469:307-12 (2013)

PMID: 23502424

Molecular biology: Choose your protein partners.

Samant RS, Workman P

490 1476-4687:351-2 (2012)

PMID: 23075983

The expanding proteome of the molecular chaperone HSP90.

Samant RS, Clarke PA, Workman P

Cell cycle (Georgetown, Tex.)
11 1551-4005:1301-8 (2012)

PMID: 22421145