Elena and Rinako present: MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis
This is a video summary presenting new findings published in The Journal of Clinical Investigation about the role of microRNA-155 in the affinity-based selection of B cells. Two of the paper’s authors, Rinako Nakagawa and Elena Vigorito, provide a personally guided tour of their results. The results of this study may extend our understanding of the pathogenesis of lymphomas and open up new therapeutic targets.
News link: A testing time: understanding more about how the ‘best’ B cells are selected
Keywords: Research, immunology, B cells, apoptosis, antibodies, germinal centre, microRNA-155, c-Myc
Date: December 2015
The inner galaxy of your genes
A video by researchers at the Babraham Institute allows a glimpse into the physical interactions occurring in the genome. Reflecting the beauty of a distant galaxy, the video shows a three-dimensional view of the contact points between the 22,000 genes in the mouse genome.
News link: Come here and be quiet!
Keywords: genome, genes, polycomb proteins, nuclear dynamics
Date: November 2015