Life Sciences Research for Lifelong Health

Bhupinder Virk

I studied at University College London (UCL) for a B.Sc. in Genetics. It was then that my love for C. elegans and my interest in the field of ageing began - it intrigued me that something so tiny could potentially answer such big questions about ageing and health. After getting my Master’s degree at Imperial College London, I moved “oop north”, to Durham University for my PhD. I used the C. elegans: E. coli (host/microbe) model to look at interactions between host and gut bacteria – focussing on how particular metabolites might influence health and ageing.

After my PhD, I went to Shanghai Jiao Tong University to set up a fully functioning C. elegans facility, as part of a collaboration project. Five months of continuous tropical monsoons and power-cuts later, I was happy to come back to the UK, for a position developing training material in the Bioinformatics group at the Babraham Institute.

Bioinformatics is pretty cool, but I missed the worms! I’m excited to have joined the Casanueva lab as a postdoc, to investigate the mechanisms underlying the widespread rewiring of proteostasis networks during early phases of the ageing process. When I’m not “worming”, I enjoy movies, theatre, live music and fitness classes.

Latest Publications

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.

Hanna CW, Taudt A, Huang J

Nature structural & molecular biology
25 1545-9985:73-82 (2018)

PMID: 29323282

An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.

Berrens RV, Andrews S, Spensberger D

Cell stem cell
21 1875-9777:694-703.e7 (2017)

PMID: 29100015

Transcription and chromatin determinants of de novo DNA methylation timing in oocytes.

Gahurova L, Tomizawa SI, Smallwood SA

Epigenetics & chromatin
10 1756-8935:25 (2017)

PMID: 28507606