Life Sciences Research for Lifelong Health
Wakelam group

Simon Rudge

Simon studied for his BSc Hons in Biochemistry at the University of Bristol. After completing his PhD in Biochemistry at the University of Birmingham, he took up post-doctoral positions in the USA. During this time, Simon started working on phospholipase D-mediated signalling in the yeast Sacchromyces cerevisae, and this work resulted in the cloning and characterisation of PLD1 and PLD2. Simon returned to the UK to join Professor Wakelam’s laboratory and continue his research on PLD enzymes. Simon regularly mentors visiting summer students in the lab, and has recently participated in the Institute’s collaboration with the newly opened University Technical College Cambridge. He enjoys being an active member of the Athena Swan and public engagement committees.

Latest Publications

Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism .

Witting M, Hastings J, Rodriguez N

Frontiers in molecular biosciences
5 2296-889X:96 (2018)

PMID: 30488036

3D growth of cancer cells elicits sensitivity to kinase inhibitors but not lipid metabolism modifiers.

Jones DT, Valli A, Haider S

Molecular cancer therapeutics
1538-8514: (2018)

PMID: 30478149

CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.

Sadej R, Lu X, Turczyk L

Journal of cell science
1477-9137: (2018)

PMID: 30257985

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.

Ezcurra M, Benedetto A, Sornda T

Current biology : CB
1879-0445: (2018)

PMID: 30100339

Extracellular vesicles : lipids as key components of their biogenesis and functions.

Record M, Silvente-Poirot S, Poirot M

Journal of lipid research
1539-7262: (2018)

PMID: 29764923

Phospholipid signaling in innate immune cells.

O'Donnell VB, Rossjohn J, Wakelam MJ

The Journal of clinical investigation
1558-8238: (2018)

PMID: 29683435

Deciphering lipid structures based on platform-independent decision rules.

Hartler J, Triebl A, Ziegl A

Nature methods
1548-7105: (2017)

PMID: 29058722

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

Farquhar MJ, Humphreys IS, Rudge SA

Journal of hepatology
1600-0641: (2017)

PMID: 28126468