Karen AndersonKaren did her PhD in Biochemistry at the Baker Medical Research Institute/Melbourne University in Australia investigating phosphatidylinositol signalling in myocardial ischaemia and reperfusion. She came to the Inositide laboratory in 1997 as part of a two year Australian NHMRC CJ Martin/RG Menzies fellowship, and remained in the lab for a further three years after being awarded a Beit Memorial Postdoctoral Fellowship. She returned to Melbourne, Australia in 2001 to complete her CJ Martin, and then subsequently a RD Wright Fellowship. Karen returned to the Inositide lab in 2004, and became a Babraham Institute Senior Research Associate in 2005. Currently, she is investigating the molecular mechanisms regulating the activation of PI3Kβ.
Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.
Koohy H, Bolland DJ, Matheson LS
19 1474-760X:126 (2018)
Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation.
Mujalli A, Chicanne G, Bertrand-Michel J
Biochimica et biophysica acta
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
Gyori D, Lim EL, Grant FM
3 2379-3708: (2018)
In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.
Durrant TN, Hutchinson JL, Heesom KJ
1 2473-9529:918-932 (2017)
Malek M, Kielkowska A, Chessa T
Gyori D, Chessa T, Hawkins PT
9 : (2017)
In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.
Bulley SJ, Droubi A, Clarke JH
Proceedings of the National Academy of Sciences of the United States of America
Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.
Ross SH, Rollings C, Anderson KE
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.
Houslay DM, Anderson KE, Chessa T
9 1937-9145:ra82 (2016)
Frej AD, Clark J, Roy CL
Molecular and cellular biology
Hawkins PT, Stephens LR
Biochemical Society transactions
44 1470-8752:307-14 (2016)
Alliouachene S, Bilanges B, Chicanne G
13 2211-1247:1881-94 (2015)