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Tamara Chessa
Latest Publications
Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.
Suire S, Baltanas FC, Segonds-Pichon A
Journal of leukocyte biology
1938-3673: (2019)
PMID: 30720883
Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors.
Tsolakos N, Durrant TN, Chessa T
Proceedings of the National Academy of Sciences of the United States of America
115 1091-6490:12176-12181 (2018)
PMID: 30442661
Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.
Koohy H, Bolland DJ, Matheson LS
Genome biology
19 1474-760X:126 (2018)
PMID: 30180872
Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation.
Mujalli A, Chicanne G, Bertrand-Michel J
Biochimica et biophysica acta
0006-3002: (2018)
PMID: 29902570
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
Gyori D, Lim EL, Grant FM
JCI insight
3 2379-3708: (2018)
PMID: 29875321
In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.
Durrant TN, Hutchinson JL, Heesom KJ
Blood advances
1 2473-9529:918-932 (2017)
PMID: 29242851
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Malek M, Kielkowska A, Chessa T
Molecular cell
1097-4164: (2017)
PMID: 29056325
Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment.
Gyori D, Chessa T, Hawkins PT
Cancers
9 : (2017)
PMID: 28273837
cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.
Cerny O, Anderson KE, Stephens LR
Journal of immunology (Baltimore, Md. : 1950)
198 1550-6606:1285-1296 (2017)
PMID: 28039302
In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.
Bulley SJ, Droubi A, Clarke JH
Proceedings of the National Academy of Sciences of the United States of America
1091-6490: (2016)
PMID: 27601656
Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.
Ross SH, Rollings C, Anderson KE
Immunity
1097-4180: (2016)
PMID: 27566939
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.
Houslay DM, Anderson KE, Chessa T
Science signaling
9 1937-9145:ra82 (2016)
PMID: 27531651