Life Sciences Research for Lifelong Health
Welch Group members

Group Members

Dr Heidi Welch

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Mrs Laraine Crossland

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Miss Elizabeth Hampson

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Dr Kirsti Hornigold

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Mr Alejandro Kauil

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Miss Polly Machin

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Miss Anna Mandel

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Miss Chiara Pantarelli

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Miss Anna Roberts

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Elpida Tsonou

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Latest Publications

Removing physiological motion from intravital and clinical functional imaging data.

Warren SC, Nobis M, Magenau A

eLife
7 2050-084X: (2018)

PMID: 29985127

Rac-GTPases and Rac-GEFs in neutrophil adhesion, migration and recruitment.

Pantarelli C, Welch HCE

European journal of clinical investigation
1365-2362:e12939 (2018)

PMID: 29682742

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

Nobis M, Herrmann D, Warren SC

Cell reports
21 2211-1247:274-288 (2017)

PMID: 28978480

Platelets in neutrophil recruitment to sites of inflammation.

Pitchford S, Pan D, Welch HC

Current opinion in hematology
1531-7048: (2016)

PMID: 27820736

Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.

Lissanu Deribe Y, Shi Y, Rai K

Proceedings of the National Academy of Sciences of the United States of America
1091-6490: (2016)

PMID: 26884185

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.

Pan D, Barber MA, Hornigold K

The Journal of biological chemistry
1083-351X: (2016)

PMID: 26792863

Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment.

Baker MJ, Pan D, Welch HC

Current opinion in hematology
23 1531-7048:44-54 (2016)

PMID: 26619317

Regulation and Function of P-Rex Family Rac-GEFs.

Welch HC

Small GTPases
2154-1256:0 (2015)

PMID: 25961466

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

Pan D, Amison RT, Riffo-Vasquez Y

Blood
1528-0020: (2014)

PMID: 25538043

A rac1-independent role for p-rex1 in melanoblasts.

Lindsay CR, Li A, Faller W

The Journal of investigative dermatology
135 1523-1747:314-8 (2015)

PMID: 25075639

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

G Damoulakis, L Gambardella, KL Rossman

Journal of cell science
127 Pt 11:2589-600 (2014)

DOI: 10.1242/jcs.153049

PMID: 24659802