Martin TurnerAfter graduating in Biochemistry from UCL Martin completed a PhD with Marc Feldmann studying the regulation of cytokine gene expression where he contributed to the basic science studies that led to the identification of TNF as a target in rheumatoid arthritis. He worked with Victor Tybulewicz at the MRC-National Institute of Medical Research where he identified elements of signal transduction necessary for the development of lymphocytes. He joined the Babraham Institute in 1997 where he continued research into signal transduction identifying roles for PI3K in lymphocyte development and activation. Some of this work underpinned the rationale for the use of inhiitors of PI3K delta in human malignancy. Recent work by his group seeks to understand how RNA-processing mechanisms control the development and function of B and T lymphocytes. He is interested in RNA-binding proteins and microRNAs and how these function within signal transduction networks to control cell differentiation and immunity.
Hodson DJ, Screen M, Turner M
Goossens P, Rodriguez-Vita J, Etzerodt A
Petkau G, Turner M
The Biochemical journal
476 1470-8728:769-778 (2019)
Bye-A-Jee H, Pugazhendhi D, Woodhouse S
8 2044-5040:37 (2018)
Transcriptome analysis of infected and bystander type 2 alveolar epithelial cells during influenza A virus infection reveals Wnt pathway downregulation.
Hancock AS, Stairiker CJ, Boesteanu AC
Journal of virology
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.
Salerno F, Engels S, van den Biggelaar M
Martínez-Riaño A, Bovolenta ER, Mendoza P
Díaz-Muñoz MD, Turner M
Frontiers in immunology
9 1664-3224:1094 (2018)
Monzón-Casanova E, Screen M, Díaz-Muñoz MD
Turner M, Díaz-Muñoz MD
Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells.
Díaz-Muñoz MD, Kiselev VY, Novère NL
8 2041-1723:530 (2017)
Tarling EJ, Clifford BL, Cheng J
The Journal of clinical investigation