Life Sciences Research for Lifelong Health

Martin Turner

After graduating in Biochemistry from UCL Martin completed a PhD with Marc Feldmann studying the regulation of cytokine gene expression where he contributed to the basic science studies that led to the identification of TNF as a target in rheumatoid arthritis. He worked with Victor Tybulewicz at the MRC-National Institute of Medical Research where he identified elements of signal transduction necessary for the development of lymphocytes. He joined the Babraham Institute in 1997 where he continued research into signal transduction identifying roles for PI3K in lymphocyte development and activation. Some of this work underpinned the rationale for the use of inhiitors of PI3K delta in human malignancy.  Recent work by his group seeks to understand how RNA-processing mechanisms control the development and function of B and T lymphocytes.  He is interested in RNA-binding proteins and microRNAs and how these function within signal transduction networks to control cell differentiation and immunity.

01223 496460

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Latest Publications

Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.

Trulley P, Snieckute G, Bekker-Jensen D

Cell reports
27 2211-1247:2859-2870.e6 (2019)

PMID: 31167133

MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells.

Arbore G, Henley T, Biggins L

Life science alliance
2 2575-1077: (2019)

PMID: 31097471

RNA binding proteins in hematopoiesis and hematological malignancy.

Hodson DJ, Screen M, Turner M

Blood
1528-0020: (2019)

PMID: 30967369

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.

Goossens P, Rodriguez-Vita J, Etzerodt A

Cell metabolism
1932-7420: (2019)

PMID: 30930171

Signalling circuits that direct early B-cell development.

Petkau G, Turner M

The Biochemical journal
476 1470-8728:769-778 (2019)

PMID: 30842310

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.

Bye-A-Jee H, Pugazhendhi D, Woodhouse S

Skeletal muscle
8 2044-5040:37 (2018)

PMID: 30526691

Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.

Salerno F, Engels S, van den Biggelaar M

Nature immunology
1529-2916: (2018)

PMID: 29988089

Antigen phagocytosis by B cells is required for a potent humoral response.

Martínez-Riaño A, Bovolenta ER, Mendoza P

EMBO reports
1469-3178: (2018)

PMID: 29987136

Uncovering the Role of RNA-Binding Proteins in Gene Expression in the Immune System.

Díaz-Muñoz MD, Turner M

Frontiers in immunology
9 1664-3224:1094 (2018)

PMID: 29875770

The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers.

Monzón-Casanova E, Screen M, Díaz-Muñoz MD

Nature immunology
1529-2916: (2018)

PMID: 29358707

RNA-binding proteins control gene expression and cell fate in the immune system.

Turner M, Díaz-Muñoz MD

Nature immunology
1529-2916: (2018)

PMID: 29348497