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Charlene Fabian
Charlene was awarded an MSci in Molecular and Cellular Biology by the University of Glasgow in 2016. As part of her course, Charlene undertook a one-year research placement within the Refractory, Respiratory and Inflammation Discover Performance Unit of GSK, where she was involved in target identification.Charlene started her PhD at the Babraham Institute in October 2016 and is funded by an MRC Industrial CASE Studentship. In collaboration with DefiniGEN, Charlene will investigate the role of epigenetic processes in the specification of pancreatic cells from human pluripotent stem cells.
Latest Publications
Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.
Andrews PW, Ben-David U, Benvenisty N
Stem cell reports
9 2213-6711:1-4 (2017)
PMID: 28700896
Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis.
Carucci N, Cacci E, Nisi PS
Royal Society open science
4 :160913 (2017)
PMID: 28484611
Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States.
Collier AJ, Panula SP, Schell JP
Cell stem cell
1875-9777: (2017)
PMID: 28343983
Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.
Freire-Pritchett P, Schoenfelder S, Várnai C
eLife
6 2050-084X: (2017)
PMID: 28332981
DNA methylation is dispensable for changes in global chromatin architecture but required for chromocentre formation in early stem cell differentiation.
Hassan-Zadeh V, Rugg-Gunn P, Bazett-Jones DP
Chromosoma
1432-0886: (2017)
PMID: 28084535
Derivation and Culture of Epiblast Stem Cell (EpiSC) Lines.
Rugg-Gunn P
Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)
PMID: 28049783
Derivation and Culture of Extra-Embryonic Endoderm Stem Cell Lines.
Rugg-Gunn P
Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093963 (2017)
PMID: 28049782
XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.
Vallot C, Patrat C, Collier AJ
Cell stem cell
1875-9777: (2016)
PMID: 27989768
Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells.
Collinson A, Collier AJ, Morgan NP
Cell reports
17 2211-1247:2700-2714 (2016)
PMID: 27926872
Crosstalk between pluripotency factors and higher-order chromatin organization.
Lopes Novo C, Rugg-Gunn PJ
Nucleus (Austin, Tex.)
1949-1042:0 (2016)
PMID: 27759487
Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.
von Meyenn F, Berrens RV, Andrews S
Developmental cell
39 1878-1551:104-115 (2016)
PMID: 27728778
The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.
Novo CL, Tang C, Ahmed K
Genes & development
1549-5477: (2016)
PMID: 27125671