Clara NovoClara obtained her Ph.D. in 2010 under the supervision of Nicola Royle (University of Leicester). The focus of her thesis was on the mechanisms that underlie MS32 minisatellite instability in telomeres. Clara was awarded Fellowships to study the replication and organisation of telomeres with Arturo Londoño-Vallejo (Institute Curie, Paris) followed by the investigation of epigenetic alterations of telomeres in cancer with Vincent Castronovo and Denis Mottet (Institute GIGA, Liege). Funded by the EpiGeneSys Network (www.epigenesys.eu), Clara joined the Babraham Institute in 2013 to study the three-dimensional organisation of the genome in stem cells and reprogramming.
Rulands S, Lee HJ, Clark SJ
Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks.
Choy MK, Javierre BM, Williams SG
9 2041-1723:2526 (2018)
Identifying Human Naïve Pluripotent Stem Cells - Evaluating State-Specific Reporter Lines and Cell-Surface Markers.
Collier AJ, Rugg-Gunn PJ
BioEssays : news and reviews in molecular, cellular and developmental biology
Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.
Novo CL, Javierre BM, Cairns J
22 2211-1247:2615-2627 (2018)
Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age-associated neurogenic decline.
Lupo G, Nisi PS, Esteve P
Naive pluripotent stem cells as a model for studying human developmental epigenomics: opportunities and limitations.
Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.
Andrews PW, Ben-David U, Benvenisty N
Stem cell reports
9 2213-6711:1-4 (2017)
Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis.
Carucci N, Cacci E, Nisi PS
Royal Society open science
4 :160913 (2017)
Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States.
Collier AJ, Panula SP, Schell JP
Cell stem cell
Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.
Freire-Pritchett P, Schoenfelder S, Várnai C
6 2050-084X: (2017)
DNA methylation is dispensable for changes in global chromatin architecture but required for chromocentre formation in early stem cell differentiation.
Hassan-Zadeh V, Rugg-Gunn P, Bazett-Jones DP
Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)