Life Sciences Research for Lifelong Health

Clara Novo

Clara obtained her Ph.D. in 2010 under the supervision of Nicola Royle (University of Leicester). The focus of her thesis was on the mechanisms that underlie MS32 minisatellite instability in telomeres. Clara was awarded Fellowships to study the replication and organisation of telomeres with Arturo Londoño-Vallejo (Institute Curie, Paris) followed by the investigation of epigenetic alterations of telomeres in cancer with Vincent Castronovo and Denis Mottet (Institute GIGA, Liege). Funded by the EpiGeneSys Network (www.epigenesys.eu), Clara joined the Babraham Institute in 2013 to study the three-dimensional organisation of the genome in stem cells and reprogramming.

Latest Publications

Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks.

Choy MK, Javierre BM, Williams SG

Nature communications
9 2041-1723:2526 (2018)

PMID: 29955040

Identifying Human Naïve Pluripotent Stem Cells - Evaluating State-Specific Reporter Lines and Cell-Surface Markers.

Collier AJ, Rugg-Gunn PJ

BioEssays : news and reviews in molecular, cellular and developmental biology
1521-1878:e1700239 (2018)

PMID: 29574793

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981

Derivation and Culture of Epiblast Stem Cell (EpiSC) Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)

PMID: 28049783

Derivation and Culture of Extra-Embryonic Endoderm Stem Cell Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093963 (2017)

PMID: 28049782