Life Sciences Research for Lifelong Health

Group Members

PeterOur group is housed within a large open plan lab that is shared with all members of the Epigenetics Programme. The open setting establishes an exciting dynamic between research groups, often leading to collaborations, training in new methods and interesting discussions. Weekly departmental meetings and seminars reinforce these close interactions.

Outside of Epigenetics, we collaborate closely with several groups within the Lymphocyte and Signalling Programmes, with a particular focus on potential interactions between signalling pathways and epigenetic processes. Our research also benefits greatly from the excellent facilities at the Babraham Institute, with state-of-the-art genomics, flow cytometry, imaging, mass spectrometry and bioinformatics.

​We maintain close links with the University of Cambridge, with affiliations at the WT-MRC Cambridge Stem Cell Institute (www.stemcells.cam.ac.uk) and the Centre for Trophoblast Research (www.trophoblast.cam.ac.uk).
 

Peter's Career

Peter joined the Babraham Institute in 2011 as a Wellcome Trust Research Career Development Fellow. Peter trained in the laboratories of Roger Pedersen (University of Cambridge) and Janet Rossant (The Hospital for Sick Children, Toronto) where he developed his interest in understanding the epigenetic regulation of stem cells and lineage specification. Peter's research is currently focused on understanding the epigenetic mechanisms that control developmental and stem cell regulation. 

Peter is also involved in the societal impact of stem cell research – working with artists, legal scholars and policy makers to examine the complex ethical and social issues surrounding new biotechnologies such as gene editing in stem cells.


 
Dr Peter Rugg-Gunn

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Mr Adam Bendall

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Miss Charlene Fabian

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Mr Andrew Malcolm

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Kate Maskalenka

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Dr Clara Novo

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Dr Claudia Semprich

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Miss Elena Stoyanova

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Latest Publications

Transcription factors make the right contacts.

Rugg-Gunn PJ

Nature cell biology
1476-4679: (2019)

PMID: 31548607

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ

Cell systems
2405-4712: (2018)

PMID: 30031774

Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks.

Choy MK, Javierre BM, Williams SG

Nature communications
9 2041-1723:2526 (2018)

PMID: 29955040

Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.

Andrews PW, Ben-David U, Benvenisty N

Stem cell reports
9 2213-6711:1-4 (2017)

PMID: 28700896

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981