Life Sciences Research for Lifelong Health
Casanueva Group members

Laetitia Chauve

Genetics and its interaction with the environment have always fascinated me. I studied biology at the University Pierre and Marie Curie and Ecole Normale Superieure in Paris, after which I did my first year of master internship in the Morimoto lab at Northwestern University. There I discovered the great model organism C. elegans and the beauty of in vivo monitoring of stress reporters. I did my second year of master internship in the Bessereau lab at Ecole Normale Superieure in Paris where I first came across the powerful genome-engineering tools based on the mobilization of the exogenous Mos1 transposon. During my PhD, I have been very interested in understanding why the stress transcription factor HSF-1 is essential for C. elegans development. I am very excited to have recently joined the Casanueva lab as a postdoc to investigate the basis for inter-individual variation in lifespan. Outside the lab, I enjoy playing listening to gipsy-jazz, playing bass guitar and bass recorder and salsa dancing.

01223 496102

Email Laetitia

Latest Publications

Multi-Omics and Genome-Scale Modeling Reveal a Metabolic Shift During C. Elegans Ageing.

Hastings J, Mains A, Virk B

Frontiers in molecular biosciences
6 2296-889X:2 (2019)

PMID: 30788345

Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism .

Witting M, Hastings J, Rodriguez N

Frontiers in molecular biosciences
5 2296-889X:96 (2018)

PMID: 30488036

Epigenetic inheritance of proteostasis and ageing.

Li C, Casanueva O

Essays in biochemistry
60 1744-1358:191-202 (2016)

PMID: 27744335

Fitness trade-offs and environmentally induced mutation buffering in isogenic C. elegans.

MO Casanueva, A Burga, B Lehner

Science (New York, N.Y.)
335 6064:82-5 (2012)

DOI: 10.1126/science.1213491

PMID: 22174126

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells.

SM Garcia, MO Casanueva, MC Silva

Genes & development
21 22:3006-16 (2007)

DOI: 10.1101/gad.1575307

PMID: 18006691

Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling.

MO Casanueva, EL Ferguson

Development (Cambridge, England)
131 9:1881-90 (2004)

DOI: 10.1242/dev.01076

PMID: 15105369