Laetitia ChauveGenetics and its interaction with the environment have always fascinated me. I studied biology at the University Pierre and Marie Curie and Ecole Normale Superieure in Paris, after which I did my first year of master internship in the Morimoto lab at Northwestern University. There I discovered the great model organism C. elegans and the beauty of in vivo monitoring of stress reporters. I did my second year of master internship in the Bessereau lab at Ecole Normale Superieure in Paris where I first came across the powerful genome-engineering tools based on the mobilization of the exogenous Mos1 transposon. During my PhD, I have been very interested in understanding why the stress transcription factor HSF-1 is essential for C. elegans development. I am very excited to have recently joined the Casanueva lab as a postdoc to investigate the basis for inter-individual variation in lifespan. Outside the lab, I enjoy playing listening to gipsy-jazz, playing bass guitar and bass recorder and salsa dancing.
Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism .
Witting M, Hastings J, Rodriguez N
Frontiers in molecular biosciences
5 2296-889X:96 (2018)
Li C, Casanueva O
Essays in biochemistry
60 1744-1358:191-202 (2016)
Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells.
W Lu, MO Casanueva, AP Mahowald
10 7:e1001357 (2012)
MO Casanueva, A Burga, B Lehner
Science (New York, N.Y.)
335 6064:82-5 (2012)
A Burga, MO Casanueva, B Lehner
480 7376:250-3 (2011)
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells.
SM Garcia, MO Casanueva, MC Silva
Genes & development
21 22:3006-16 (2007)
Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling.
MO Casanueva, EL Ferguson
Development (Cambridge, England)
131 9:1881-90 (2004)
At least two receptors of asymmetric acetylcholinesterase are present at the synaptic basal lamina of Torpedo electric organ.
OI Casanueva, P Deprez, T García-Huidobro
Biochemical and biophysical research communications
250 2:312-7 (1998)
A major portion of synaptic basal lamina acetylcholinesterase is detached by high salt- and heparin-containing buffers from rat diaphragm muscle and Torpedo electric organ.
Casanueva OI, García-Huidobro T, Campos EO
The Journal of biological chemistry
273 0021-9258:4258-65 (1998)
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.
NC Inestrosa, A Alvarez, CA Pérez
16 4:881-91 (1996)