Life Sciences Research for Lifelong Health
Casanueva Group members

Sharlene Murdoch

I was born and raised in Montreal, Canada where I developed a love for hockey (or ice hockey as you call it over here) and maple syrup. I studied at McGill University where I obtained a B. Sc. in Biology and went on to a Master’s in Human Genetics researching the genetic basis of Recurrent Familial Hydatidiform Moles under Dr Rima Slim. After completing this degree I went on to indulge my other loves of travel and teaching in South Korea where I taught English as a Second Language in Seoul. After five years working and having exciting adventures in exotic locales I missed being a scientist and decided to move on to an even more exotic land: Scotland. While studying for another Master’s degree at the University of Aberdeen I developed affection for rugby and Haggis though not so much for Scottish weather. After graduating I got a job as a Research Technician at King’s College London, there I was introduced to our model organism C. elegans. After two years in London I was happy to leave the hustle and bustle and overcrowded tubes to come to Cambridge join the Casanueva lab as a Senior Research Assistant. When not wrangling worms, I enjoy fitness, travel and playing board games. I’m happy to have made England my new home but still really miss hockey and decent maple syrup.

01223 496411

Email Sharlene

Latest Publications

Multi-Omics and Genome-Scale Modeling Reveal a Metabolic Shift During C. Elegans Ageing.

Hastings J, Mains A, Virk B

Frontiers in molecular biosciences
6 2296-889X:2 (2019)

PMID: 30788345

Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism .

Witting M, Hastings J, Rodriguez N

Frontiers in molecular biosciences
5 2296-889X:96 (2018)

PMID: 30488036

Epigenetic inheritance of proteostasis and ageing.

Li C, Casanueva O

Essays in biochemistry
60 1744-1358:191-202 (2016)

PMID: 27744335

Fitness trade-offs and environmentally induced mutation buffering in isogenic C. elegans.

MO Casanueva, A Burga, B Lehner

Science (New York, N.Y.)
335 6064:82-5 (2012)

DOI: 10.1126/science.1213491

PMID: 22174126

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells.

SM Garcia, MO Casanueva, MC Silva

Genes & development
21 22:3006-16 (2007)

DOI: 10.1101/gad.1575307

PMID: 18006691

Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling.

MO Casanueva, EL Ferguson

Development (Cambridge, England)
131 9:1881-90 (2004)

DOI: 10.1242/dev.01076

PMID: 15105369