Life Sciences Research for Lifelong Health

Jonathan Gilley

Jon joined Michael's group in 2004. After completing his Ph.D. studies in Mike Fried’s groups at the Imperial Cancer Research Fund (now the Cancer Research UK, London Research Institute) in 1999, he studied aspects of developmental neuronal cell death in Jonathan Ham’s group as a postdoc at the Institute of Child Health, London (1999-2004). At Babraham he has been investigating the molecular mechanisms involved in axon degeneration after injury and in disease as well as generating and characterizing new mouse models of dementia.

Latest Publications

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.

White MA, Lin Z, Kim E

Acta neuropathologica communications
7 2051-5960:166 (2019)

PMID: 31661035

NAD cleavage activity by animal and plant TIR domains in cell death pathways.

Horsefield S, Burdett H, Zhang X

Science (New York, N.Y.)
365 1095-9203:793-799 (2019)

PMID: 31439792

Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia.

Huppke P, Wegener E, Gilley J

Experimental neurology
320 1090-2430:112958 (2019)

PMID: 31132363

A closer look at neuron interaction with track-etched microporous membranes.

George JH, Nagel D, Waller S

Scientific reports
8 2045-2322:15552 (2018)

PMID: 30341335

P7C3-A20 neuroprotection is independent of Wallerian degeneration in primary neuronal culture.

Hill CS, Menon DK, Coleman MP

1473-558X: (2018)

PMID: 30334859

Low levels of NMNAT2 compromise axon development and survival.

Gilley J, Mayer P, Yu G

Human molecular genetics
1460-2083: (2018)

PMID: 30304512

Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.

Adalbert R, Milde S, Durrant C

Neurobiology of aging
68 1558-1497:68-75 (2018)

PMID: 29729423

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

White MA, Kim E, Duffy A

Nature neuroscience
1546-1726: (2018)

PMID: 29556029