Life Sciences Research for Lifelong Health
lab photo hero

Rafeah Alam

Rafeah graduated from University College London in 2010 with a BSc in Pharmacology. This was followed by a Master’s in Drug Discovery Skills at Kings College London in 2011. As part of her MSc she spent 5 months at AstraZeneca where she worked on assessing the impact of acute cytotoxic treatment on signalling pathways in human tumour models. Following her MSc degree, she spent 2 years working at UCB as a Research Assistant exploring the in vivo potential of some of the therapeutics focused on autoimmune diseases. Her current project as a PhD student at the Babraham Institute involves investigating the effect of overactive p110δ activity on T cell function in a model of a newly discovered primary immunodeficiency ‘’Activated PI3Kδ syndrome’’.

Latest Publications

Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease.

Paz K, Flynn R, Du J

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
1600-6143: (2019)

PMID: 30748099

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA

Journal of immunology (Baltimore, Md. : 1950)
1550-6606: (2019)

PMID: 30692213

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H

47 1097-4180:875-889.e10 (2017)

PMID: 29166588

Multi-tissue DNA methylation age predictor in mouse.

Stubbs TM, Bonder MJ, Stark AK

Genome biology
18 1474-760X:68 (2017)

PMID: 28399939

Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy.

Okkenhaug K, Graupera M, Vanhaesebroeck B

Cancer discovery
2159-8290: (2016)

PMID: 27655435