Life Sciences Research for Lifelong Health
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Anita Chandra

Anita is a medic who obtained her primary medical degree from the University of Cambridge in 1998.  Following general medical training where she obtained membership of the Royal College of Physicians (MRCP), she commenced her training in Clinical Immunology, initially in Newcastle upon Tyne and soon thereafter, at Addenbrooke’s hospital in Cambridge. She subsequently obtained her Fellowship of the Royal College of Pathologists (FRCPath) and currently works as an Honorary Consultant at Addenbrooke’s hospital in Clinical Immunology. Her clinical interests involve the management and care of patients with primary and secondary immunodeficiency.

Anita obtained her PhD from the University of Cambridge following work on B cell biology and antibody diversification in the Laboratory of Molecular Biology under the supervision of Professor Michael Neuberger and Dr Cristina Rada. She is currently working as a Wellcome Trust funded Postdoctoral Clinical Fellow in the Okkenhaug lab, focusing on the role of PI3Ks in human and murine immunity and susceptibility to infections. She has a particular interest in a group of patients with an activating mutation in PI3K delta (APDS) and will be complementing basic mechanistic research in this area with clinical trials using selective PI3K delta inhibitors in patients.

01223 496388

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Latest Publications

Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease.

Paz K, Flynn R, Du J

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
1600-6143: (2019)

PMID: 30748099

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA

Journal of immunology (Baltimore, Md. : 1950)
1550-6606: (2019)

PMID: 30692213

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H

Immunity
47 1097-4180:875-889.e10 (2017)

PMID: 29166588

Multi-tissue DNA methylation age predictor in mouse.

Stubbs TM, Bonder MJ, Stark AK

Genome biology
18 1474-760X:68 (2017)

PMID: 28399939

Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy.

Okkenhaug K, Graupera M, Vanhaesebroeck B

Cancer discovery
2159-8290: (2016)

PMID: 27655435