Life Sciences Research for Lifelong Health

Simon Walker

Simon obtained his first degree in Biochemistry at Heriot-Watt University in Edinburgh before moving to the John Innes Centre in Norwich where he studied for his PhD under the supervision of Allan Downie looking at the role of calcium signalling during legume symbiosis.

Simon then went to work as a postdoc for four years in Pete Cullen's lab in the Department of Biochemistry at Bristol University where he investigated the GAP1 family of ras GTPase-activating proteins.

​Having become interested in the application of imaging technologies to answer biological quesions Simon moved to the Babraham Institute in 2004 where he helped establish the core Imaging Facility.

Simon now manages the Facility which has over 100 registered users based within the Institute and an increasing number of commercial users based both on and off campus.

01223 496618

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Facility Members

Latest Publications

Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy.

Ktistakis NT, Walker SA, Karanasios E

Oncotarget
1949-2553: (2016)

PMID: 27829241

Dynamics of mTORC1 activation in response to amino acids.

Manifava M, Smith M, Rotondo S

eLife
5 2050-084X: (2016)

PMID: 27725083

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.

Karanasios E, Walker SA, Okkenhaug H

Nature communications
7 2041-1723:12420 (2016)

PMID: 27510922

Localizing the lipid products of PI3Kγ in neutrophils.

Norton L, Lindsay Y, Deladeriere A

Advances in biological regulation
2212-4934: (2015)

PMID: 26596865

A novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I.

Petrini E, Baillet V, Cridge J

Journal of cell science
1477-9137: (2015)

PMID: 26345368

Etoposide Induces Nuclear Re-Localisation of AID.

LJ Lambert, S Walker, J Feltham

PloS one
8 12:e82110 (2013)

DOI: 10.1371/journal.pone.0082110

PMID: 24324754

Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

Karanasios E, Stapleton E, Manifava M

Journal of cell science
126 1477-9137:5224-38 (2013)

PMID: 24013547

Live cell imaging of early autophagy events: omegasomes and beyond.

E Karanasios, E Stapleton, SA Walker

Journal of visualized experiments : JoVE
77: (2013)

DOI: 10.3791/50484

PMID: 23929131

Characteristics and requirements of basal autophagy in HEK 293 cells.

Musiwaro P, Smith M, Manifava M

Autophagy
9 1554-8635:1407-17 (2013)

PMID: 23800949