Bhupinder VirkI studied at University College London (UCL) for a B.Sc. in Genetics. It was then that my love for C. elegans and my interest in the field of ageing began - it intrigued me that something so tiny could potentially answer such big questions about ageing and health. After getting my Master’s degree at Imperial College London, I moved “oop north”, to Durham University for my PhD. I used the C. elegans: E. coli (host/microbe) model to look at interactions between host and gut bacteria – focussing on how particular metabolites might influence health and ageing.
After my PhD, I went to Shanghai Jiao Tong University to set up a fully functioning C. elegans facility, as part of a collaboration project. Five months of continuous tropical monsoons and power-cuts later, I was happy to come back to the UK, for a position developing training material in the Bioinformatics group at the Babraham Institute.
Bioinformatics is pretty cool, but I missed the worms! I’m excited to have joined the Casanueva lab as a postdoc, to investigate the mechanisms underlying the widespread rewiring of proteostasis networks during early phases of the ageing process. When I’m not “worming”, I enjoy movies, theatre, live music and fitness classes.
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.
Hahn O, Grönke S, Stubbs TM
18 1474-760X:56 (2017)
Milagre I, Stubbs TM, King MR
18 2211-1247:1079-1089 (2017)
DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids.
Canovas S, Ivanova E, Romar R
6 2050-084X: (2017)
Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells.
Collinson A, Collier AJ, Morgan NP
17 2211-1247:2700-2714 (2016)
Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.
von Meyenn F, Berrens RV, Andrews S
39 1878-1551:104-115 (2016)
MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs.
Wood CD, Veenstra H, Khasnis S
5 2050-084X: (2016)
Krueger F, Andrews SR
5 :1479 (2016)
Bolland DJ, Koohy H, Wood AL
15 2211-1247:2475-87 (2016)
Galloway A, Saveliev A, Łukasiak S
Science (New York, N.Y.)
352 1095-9203:453-9 (2016)
Wingett S, Ewels P, Furlan-Magaril M
4 2046-1402:1310 (2015)
Hanna CW, Peñaherrera MS, Saadeh H
Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets.
Sandovici I, Hammerle CM, Cooper WN
59 1432-0428:502-11 (2016)