Life Sciences Research for Lifelong Health

Group Members

Dr Simon Cook

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Dr Anne Ashford

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Miss Kathy Balmanno

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Miss Hasse Bossenbroek

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Dr Rebecca Gilley

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Miss Rachael Huntly

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Dr Hannah Johnson

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Dr Andrew Kidger

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Dr Pamela Lochhead

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Miss Emma Minihane

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Mr Richard Odle

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Mr Jack Prescott

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Dr Diane Proudfoot

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Miss Jayeta Saxena

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Mr James Sipthorp

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Miss Kate Stuart

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Latest Publications

Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.

Newman R, Ahlfors H, Saveliev A

Nature immunology
1529-2916: (2017)

PMID: 28394372

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

Galloway A, Saveliev A, Łukasiak S

Science (New York, N.Y.)
352 1095-9203:453-9 (2016)

PMID: 27102483

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.

Lochhead PA, Clark J, Wang LZ

Cell cycle (Georgetown, Tex.)
15 1551-4005:506-18 (2016)

PMID: 26959608

Maternal DNA Methylation Regulates Early Trophoblast Development.

Branco MR, King M, Perez-Garcia V

Developmental cell
36 1878-1551:152-63 (2016)

PMID: 26812015

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.

Caunt CJ, Sale MJ, Smith PD

Nature reviews. Cancer
15 1474-1768:577-92 (2015)

PMID: 26399658

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.

Ashford AL, Dunkley TP, Cockerill M

Cellular and molecular life sciences : CMLS
1420-9071: (2015)

PMID: 26346493