Life Sciences Research for Lifelong Health
Len Stephens' and Phill Hawkins' research group

Sabine Suire

Sabine did her BSc degree at the University of Angers and Masters and PhD in Cell Biology and Physiology at P et M Curie -Paris 6. Her PhD practical work took place at Nouzilly, INRA under the supervision of F Guillou and focused on the regulation of transferrin gene by the follitropin in Sertoli cells. She moved to UK for her first post-doc at the Babraham Institute (F. Stewart) for studying the role of lipocalin on early stage of mare pregnancy. At the dawn of the new millennium, she moved to the Inositide lab, where she has been working on the regulation of PI3Kγ by Ras in mouse neutrophils ever since.

Latest Publications

In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.

Bulley SJ, Droubi A, Clarke JH

Proceedings of the National Academy of Sciences of the United States of America
1091-6490: (2016)

PMID: 27601656

Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.

Houslay DM, Anderson KE, Chessa T

Science signaling
9 1937-9145:ra82 (2016)

PMID: 27531651

The inositol-3-phosphate synthase biosynthetic enzyme has distinct catalytic and metabolic roles.

Frej AD, Clark J, Roy CL

Molecular and cellular biology
1098-5549: (2016)

PMID: 26951199

Emerging evidence of signalling roles for PI(3,4)P2 in Class I and II PI3K-regulated pathways.

Hawkins PT, Stephens LR

Biochemical Society transactions
44 1470-8752:307-14 (2016)

PMID: 26862220

Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.

Alliouachene S, Bilanges B, Chicanne G

Cell reports
13 2211-1247:1881-94 (2015)

PMID: 26655903

Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells.

Anderson KE, Juvin V, Clark J

Advances in biological regulation
2212-4934: (2015)

PMID: 26639089

Localizing the lipid products of PI3Kγ in neutrophils.

Norton L, Lindsay Y, Deladeriere A

Advances in biological regulation
2212-4934: (2015)

PMID: 26596865

The cytotoxic T cell proteome and its shaping by the kinase mTOR.

Hukelmann JL, Anderson KE, Sinclair LV

Nature immunology
1529-2916: (2015)

PMID: 26551880

The regulatory subunits of PI3Kγ control distinct neutrophil responses.

Deladeriere A, Gambardella L, Pan D

Science signaling
8 1937-9145:ra8 (2015)

PMID: 25605974