Elise JacquinElise graduated in 2009 with an MSc in Biochemistry, Cellular and Molecular biology from the University of Besancon, France. She was awarded her PhD in 2013 after studying molecular markers of precancerous and cancerous lesions associated with Human Papillomaviruses. Meanwhile, she worked on the characterization of an alternative pathway of carcinogenesis involving the uptake of apoptotic HPV-positive cancer cells by human primary fibroblasts. This last experience led Elise to grow an interest in macroendocytic processes and their consequences in cells. Elise joined Oliver Florey’s lab in October 2014 for her postdoctoral training funded by Cancer Research UK. She currently investigates the molecular mechanisms which underlie the unconventional activity of autophagy proteins during macroendocytic processes such as phagocytosis and entosis. Since she has joined the lab, Elise has presented her work during meetings in the UK, in Spain and in France.
Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation.
Jacquin E, Leclerc-Mercier S, Judon C
Krishna S, Palm W, Lee Y
38 1878-1551:536-47 (2016)
3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy.
Russell MR, Lerner TR, Burden JJ
Journal of cell science
Klionsky DJ, Abdelmohsen K, Abe A
12 1554-8635:1-222 (2016)
Florey O, Gammoh N, Kim SE
Durgan J, Tao G, Walters MS
16 1469-3178:87-96 (2015)
Sun Q, Luo T, Ren Y
24 1748-7838:1299-310 (2014)
TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation.
Nair-Gupta P, Baccarini A, Tung N
158 1097-4172:506-21 (2014)
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.
N Gammoh, O Florey, M Overholtzer
Nature structural & molecular biology
20 2:144-9 (2013)
O Florey, M Overholtzer
Trends in cell biology
22 7:374-80 (2012)
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes.
O Florey, SE Kim, CP Sandoval
Nature cell biology
13 11:1335-43 (2011)