Katherine FletcherI studied Biochemistry at Bristol University where I developed my interest in molecular biology. After graduating I took some time to assess my next career move, taking time to volunteer in various charities and to carry out a social research project in Ghana. I returned to science when an opportunity arose for a summer internship at The Babraham Institute. This sparked my passion to begin my research career and led to a research assistant job, at the Institute, working on a full genome screen looking for autophagy enhancers and inhibitors in Nicholas Ktistakis’ lab.
I am currently funded, with a four year BBSRC studentship (starting October 2014), to carry out research in the group of Oliver Florey investigating mechanisms surrounding the autophagy related protein Atg16L1.
I am actively involved in public engagement events organised by The Babraham Institute and I have particularly enjoyed School’s day and going into local schools to deliver teaching about the science of the Institute. I look forward to being involved in further exciting opportunities to communicate science to the public and discuss the ethics and implications of our research.
Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation.
Jacquin E, Leclerc-Mercier S, Judon C
Krishna S, Palm W, Lee Y
38 1878-1551:536-47 (2016)
3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy.
Russell MR, Lerner TR, Burden JJ
Journal of cell science
Klionsky DJ, Abdelmohsen K, Abe A
12 1554-8635:1-222 (2016)
Florey O, Gammoh N, Kim SE
Durgan J, Tao G, Walters MS
16 1469-3178:87-96 (2015)
Sun Q, Luo T, Ren Y
24 1748-7838:1299-310 (2014)
TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation.
Nair-Gupta P, Baccarini A, Tung N
158 1097-4172:506-21 (2014)
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.
N Gammoh, O Florey, M Overholtzer
Nature structural & molecular biology
20 2:144-9 (2013)
O Florey, M Overholtzer
Trends in cell biology
22 7:374-80 (2012)
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes.
O Florey, SE Kim, CP Sandoval
Nature cell biology
13 11:1335-43 (2011)