Life Sciences Research for Lifelong Health

Group Members

Dr Nick Ktistakis

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Mr Qashif Ahmed

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Mr Valerio Benedetti

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Miss Maria Manifava

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Mr Ronak Shah

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Mr Matthew Smith

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Miss Sara Valladoid

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Mr Jason Yu

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Latest Publications

Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy.

Ktistakis NT, Walker SA, Karanasios E

Oncotarget
1949-2553: (2016)

PMID: 27829241

Dynamics of mTORC1 activation in response to amino acids.

Manifava M, Smith M, Rotondo S

eLife
5 2050-084X: (2016)

PMID: 27725083

Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.

Ohashi Y, Soler N, García Ortegón M

Autophagy
1554-8635:0 (2016)

PMID: 27630019

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.

Karanasios E, Walker SA, Okkenhaug H

Nature communications
7 2041-1723:12420 (2016)

PMID: 27510922

Digesting the Expanding Mechanisms of Autophagy.

Ktistakis NT, Tooze SA

Trends in cell biology
1879-3088: (2016)

PMID: 27050762

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A

Autophagy
12 1554-8635:1-222 (2016)

PMID: 26799652

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.

Rostislavleva K, Soler N, Ohashi Y

Science (New York, N.Y.)
350 1095-9203:aac7365 (2015)

PMID: 26450213

ERES: sites for autophagosome biogenesis and maturation?

Sanchez-Wandelmer J, Ktistakis NT, Reggiori F

Journal of cell science
128 1477-9137:185-192 (2015)

PMID: 25568152

Live-cell imaging for the assessment of the dynamics of autophagosome formation: Focus on early steps.

Karanasios E, Ktistakis NT

Methods (San Diego, Calif.)
1095-9130: (2014)

PMID: 25498007

Dynamics of autophagosome formation: a pulse and a sequence of waves.

Ktistakis NT, Karanasios E, Manifava M

Biochemical Society transactions
42 1470-8752:1389-95 (2014)

PMID: 25233420