Ciaran HillCiaran graduated first in his year from Barts and the Royal London medical school in 2007. After completing an MSc in Clincal Neuroscience with distinction at UCL he trained in Neurosurgery in North London. He holds the post of Honorary Senior Lecturer in Clinical Neuroscience at UCL and works as a pre-hospital doctor for London Air Ambulance.
He is currently a visiting student supervised by Dr Michael Coleman and Professor David Menon from the Brain Repair Centre in Cambridge. Ciaran is undertaking a Wellcome Trust funded PhD looking into the molecular mechanisms of traumatic axonal injury and their links to neurodegeneration. It is hoped this will open new avenues to help treat this common condition. Outside of work Ciaran enjoys high-altitude mountaineering and despite no natural ability he refuses to give up trying to learn Persian.
NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.
Di Stefano M, Loreto A, Orsomando G
Current biology : CB
KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons.
Hung CO, Coleman MP
Traffic (Copenhagen, Denmark)
Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice.
Harwell CS, Coleman MP
11 1750-1326:44 (2016)
Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies.
Clark DE, Waszkowycz B, Wong M
Bioorganic & medicinal chemistry letters
Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.
Gilley J, Ando K, Seereeram A
Neurobiology of aging
39 1558-1497:1-18 (2016)
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.
Rodríguez-Martín T, Pooler AM, Lau DH
Neurobiology of disease
85 1095-953X:1-10 (2015)
Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.
Mundinger TO, Cooper E, Coleman MP
American journal of physiology. Endocrinology and metabolism
309 1522-1555:E246-55 (2015)
Gilley J, Orsomando G, Nascimento-Ferreira I
10 2211-1247:1974-81 (2015)
Axonal transport declines with age in two distinct phases separated by a period of relative stability.
Milde S, Adalbert R, Elaman MH
Neurobiology of aging
The Axon-Protective WLD(S) Protein Partially Rescues Mitochondrial Respiration and Glycolysis After Axonal Injury.
Godzik K, Coleman MP
Journal of molecular neuroscience : MN
Di Stefano M, Nascimento-Ferreira I, Orsomando G
Cell death and differentiation
Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2).
Milde S, Coleman MP
The Journal of biological chemistry
289 1083-351X:32858-70 (2014)