Life Sciences Research for Lifelong Health

Jonathan Gilley

Jon joined Michael's group in 2004. After completing his Ph.D. studies in Mike Fried’s groups at the Imperial Cancer Research Fund (now the Cancer Research UK, London Research Institute) in 1999, he studied aspects of developmental neuronal cell death in Jonathan Ham’s group as a postdoc at the Institute of Child Health, London (1999-2004). At Babraham he has been investigating the molecular mechanisms involved in axon degeneration after injury and in disease as well as generating and characterizing new mouse models of dementia.

Latest Publications

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.

Gilley J, Ando K, Seereeram A

Neurobiology of aging
39 1558-1497:1-18 (2016)

PMID: 26923397

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.

Rodríguez-Martín T, Pooler AM, Lau DH

Neurobiology of disease
85 1095-953X:1-10 (2015)

PMID: 26459111

Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.

Mundinger TO, Cooper E, Coleman MP

American journal of physiology. Endocrinology and metabolism
309 1522-1555:E246-55 (2015)

PMID: 26037249

Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.

Gilley J, Orsomando G, Nascimento-Ferreira I

Cell reports
10 2211-1247:1974-81 (2015)

PMID: 25818290

Axonal transport declines with age in two distinct phases separated by a period of relative stability.

Milde S, Adalbert R, Elaman MH

Neurobiology of aging
1558-1497: (2014)

PMID: 25443288

The Axon-Protective WLD(S) Protein Partially Rescues Mitochondrial Respiration and Glycolysis After Axonal Injury.

Godzik K, Coleman MP

Journal of molecular neuroscience : MN
1559-1166: (2014)

PMID: 25352062

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration.

Di Stefano M, Nascimento-Ferreira I, Orsomando G

Cell death and differentiation
1476-5403: (2014)

PMID: 25323584