Life Sciences Research for Lifelong Health

Sven Sewitz



01223 496509

Email Sven

Latest Publications

Platelet function is modified by common sequence variation in megakaryocyte super enhancers.

Petersen R, Lambourne JJ, Javierre BM

Nature communications
8 2041-1723:16058 (2017)

PMID: 28703137

Cell-cycle dynamics of chromosomal organization at single-cell resolution.

Nagano T, Lubling Y, Várnai C

Nature
547 1476-4687:61-67 (2017)

PMID: 28682332

Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation.

Siersbæk R, Madsen JGS, Javierre BM

Molecular cell
66 1097-4164:420-435.e5 (2017)

PMID: 28475875

GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data.

Mifsud B, Martincorena I, Darbo E

PloS one
12 1932-6203:e0174744 (2017)

PMID: 28379994

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.

Aymard F, Aguirrebengoa M, Guillou E

Nature structural & molecular biology
1545-9985: (2017)

PMID: 28263325

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP

Cell
167 1097-4172:1369-1384.e19 (2016)

PMID: 27863249

Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Martin P, McGovern A, Massey J

PloS one
11 1932-6203:e0166923 (2016)

PMID: 27861577

Defining cell type with chromatin profiling.

Spivakov M, Fraser P

Nature biotechnology
34 1546-1696:1126-1128 (2016)

PMID: 27824844

Turning the tide on 3D nuclear organization.

Fraser P

Nature reviews. Molecular cell biology
1471-0080: (2016)

PMID: 27808275

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P

Genome biology
17 1474-760X:212 (2016)

PMID: 27799070