Life Sciences Research for Lifelong Health

Group Members

Mr Stephen Bevan

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Dr Jonathan Cairns

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Mr Andrew Dimond

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Dr Biola Javierre

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Dr Hashem Koohy

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Dr Wing Leung

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Dr Valeriya Malysheva

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Mr Marco Michalski

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Dr Jorg Morf

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Clare Murnane

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Dr Takashi Nagano

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Dr Stefan Schoenfelder

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Dr Sven Sewitz

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Dr Csilla Varnai

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Dr Steven Wingett

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Dr Peter Fraser

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Latest Publications

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.

Aymard F, Aguirrebengoa M, Guillou E

Nature structural & molecular biology
1545-9985: (2017)

PMID: 28263325

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP

Cell
167 1097-4172:1369-1384.e19 (2016)

PMID: 27863249

Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Martin P, McGovern A, Massey J

PloS one
11 1932-6203:e0166923 (2016)

PMID: 27861577

Defining cell type with chromatin profiling.

Spivakov M, Fraser P

Nature biotechnology
34 1546-1696:1126-1128 (2016)

PMID: 27824844

Turning the tide on 3D nuclear organization.

Fraser P

Nature reviews. Molecular cell biology
1471-0080: (2016)

PMID: 27808275

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P

Genome biology
17 1474-760X:212 (2016)

PMID: 27799070

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.

Pancaldi V, Carrillo-de-Santa-Pau E, Javierre BM

Genome biology
17 1474-760X:152 (0)

PMID: 27391817

CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data.

Cairns J, Freire-Pritchett P, Wingett SW

Genome biology
17 1474-760X:127 (2016)

PMID: 27306882

HiCUP: pipeline for mapping and processing Hi-C data.

Wingett S, Ewels P, Furlan-Magaril M

F1000Research
4 2046-1402:1310 (2015)

PMID: 26835000

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.

Martin P, McGovern A, Orozco G

Nature communications
6 2041-1723:10069 (2015)

PMID: 26616563

Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell.

Nagano T, Lubling Y, Yaffe E

Nature protocols
10 1750-2799:1986-2003 (2015)

PMID: 26540590