Life Sciences Research for Lifelong Health

Group Members

Dr Mikhail Spivakov

Mr Pawel Bednarz

Dr Jonathan Cairns

Miss Lina Dobnikar

Dr Paula Freire Pritchett

Dr Hashem Koohy

Joanna Mitchelmore

Michiel Thiecke


Latest Publications

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

6 2050-084X: (2017)

PMID: 28332981

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP

167 1097-4172:1369-1384.e19 (2016)

PMID: 27863249

Defining cell type with chromatin profiling.

Spivakov M, Fraser P

Nature biotechnology
34 1546-1696:1126-1128 (2016)

PMID: 27824844

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.

Pancaldi V, Carrillo-de-Santa-Pau E, Javierre BM

Genome biology
17 1474-760X:152 (0)

PMID: 27391817

CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data.

Cairns J, Freire-Pritchett P, Wingett SW

Genome biology
17 1474-760X:127 (2016)

PMID: 27306882

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination.

Bolland DJ, Koohy H, Wood AL

Cell reports
15 2211-1247:2475-87 (2016)

PMID: 27264181

CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets.

Schofield EC, Carver T, Achuthan P

Bioinformatics (Oxford, England)
32 1367-4811:2511-3 (2016)

PMID: 27153610

Dynamic Reorganization of Extremely Long-Range Promoter-Promoter Interactions between Two States of Pluripotency.

Joshi O, Wang SY, Kuznetsova T

Cell stem cell
17 1875-9777:748-57 (2015)

PMID: 26637943

A novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I.

Petrini E, Baillet V, Cridge J

Journal of cell science
1477-9137: (2015)

PMID: 26345368

A comparison of peak callers used for DNase-seq Data

H Koohy, TA Down, M Spivakov

9 5:e96303 (2014)

DOI: 10.1371/journal.pone.0096303

PMID: 24810143