Rebecca BerrensShort Biography
2013 - current: PhD student at Cambridge University, Babraham Institute (Funded by Gates Cambridge scholarship)
2010 - 2012: Master in Molecular Biotechnology at Heidelberg University
2007 - 2010: Bachelor in Molecular Cell Biology at Heidelberg University
Research Interests and Activities
I am interested in transposon regulation and its role in epigenetic reprogramming during early embryonic development in mammals.
Transposons are known to be highly guarded by DNA methylation in somatic cells, though histone modifications and small RNAs have also been found to play a role in keeping these repeat elements in check.
My work focuses on the effect of the genome wide erasure of epigenetic marks in the early embryo, on transposon activity. Specifically, the dynamics and interplay between DNA methylation, histone modifications and, my main area of interest- small RNAs, which lead to the silencing of transposons.
Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
Kirschner K, Chandra T, Kiselev V
19 2211-1247:1503-1511 (2017)
Vasiliauskaitė L, Vitsios D, Berrens RV
Nature structural & molecular biology
Stubbs TM, Bonder MJ, Stark AK
18 1474-760X:68 (2017)
Angermueller C, Lee HJ, Reik W
18 1474-760X:67 (2017)
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.
Hahn O, Grönke S, Stubbs TM
18 1474-760X:56 (2017)
Kiselev VY, Kirschner K, Schaub MT
Iurlaro M, von Meyenn F, Reik W
Current opinion in genetics & development
43 1879-0380:101-109 (2017)
Langie SA, Cameron KM, Ficz G
8 : (2017)
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).
Clark SJ, Smallwood SA, Lee HJ
12 1750-2799:534-547 (2017)
Kalkan T, Olova N, Roode M
Development (Cambridge, England)
Milagre I, Stubbs TM, King MR
18 2211-1247:1079-1089 (2017)
Selleri L, Bartolomei MS, Bickmore WA
12 1553-7404:e1006485 (2016)