Christel KruegerShort biography
- 2005 - current: Post-Doctoral Research Associate, Babraham Institute, Cambridge, UK (funded by personal fellowships from EMBO, DFG and CTR, as well as by BBSRC and Wellcome Trust grants)
- 2001 - 2004: PhD in Biology, Friedrich-Alexander Universitaet Erlangen, Germany (State of Bavaria Fellowship)
Research Interests and Activities
I have a fascination with life, especially with the beginning of it. When the parental gametes meet to form a zygote, a new organism comes into being. A number of biologically drastic measures are taken both before and after fertilisation to turn the old generation into a new one: Not only is the age of the parental cells set to zero, but also are two highly specialised cells (the gametes) turned into one all-rounder (the totipotent zygote). Being a molecular biologist, I’m interested in how this is brought about on a molecular level, and currently I’m studying a potential mechanism of bringing about totipotency.
Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
Kirschner K, Chandra T, Kiselev V
19 2211-1247:1503-1511 (2017)
Vasiliauskaitė L, Vitsios D, Berrens RV
Nature structural & molecular biology
Stubbs TM, Bonder MJ, Stark AK
18 1474-760X:68 (2017)
Angermueller C, Lee HJ, Reik W
18 1474-760X:67 (2017)
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.
Hahn O, Grönke S, Stubbs TM
18 1474-760X:56 (2017)
Kiselev VY, Kirschner K, Schaub MT
Iurlaro M, von Meyenn F, Reik W
Current opinion in genetics & development
43 1879-0380:101-109 (2017)
Langie SA, Cameron KM, Ficz G
8 : (2017)
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).
Clark SJ, Smallwood SA, Lee HJ
12 1750-2799:534-547 (2017)
Kalkan T, Olova N, Roode M
Development (Cambridge, England)
Milagre I, Stubbs TM, King MR
18 2211-1247:1079-1089 (2017)
Selleri L, Bartolomei MS, Bickmore WA
12 1553-7404:e1006485 (2016)