Life Sciences Research for Lifelong Health

Mario Iurlaro

Short Biography:

• 2016-current: Postdoctoral Research Scientist, Babraham Institute, Cambridge
• 2012-2016: PhD in Biological Sciences, Universtiy of Cambridge, Babraham Institute
• 2008-2011: MSc in Molecular Biotechnologies, University of Bologna, Italy
• 2005-2008: BSc in Biotechnologies, University of Bologna, Italy

I was born and raised in the sunny city of Taranto in Puglia, Italy. I studied in Bologna where I obtained a BSc in Biotechnologies with a thesis on transcriptional regulation in bacteria. I then went on to a Master’s in Molecular Biotechnologies, during which I spent 1 year at the University of Oxford studying molecular mechanisms underlying innate immune response in Drosophila. I finally joined the Reik Lab at the Babraham Institute, first as a visiting student and then as a PhD student, where I’ve been working on the molecular mechanisms linking DNA demethylation and pluripotency, and on the biological function of the oxidised derivatives of 5-methylcytosine.

In my spare time I enjoy travelling, movies and basketball. I’ve also been a proud member of the Babraham Institute football club since my first week here and I have the astonishing record of 1 goal in 4 years.

Latest Publications

Tracking the embryonic stem cell transition from ground state pluripotency.

Kalkan T, Olova N, Roode M

Development (Cambridge, England)
1477-9129: (2017)

PMID: 28174249

Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming.

Milagre I, Stubbs TM, King MR

Cell reports
18 2211-1247:1079-1089 (2017)

PMID: 28147265

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

Selleri L, Bartolomei MS, Bickmore WA

PLoS genetics
12 1553-7404:e1006485 (2016)

PMID: 27977680

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

Stepper P, Kungulovski G, Jurkowska RZ

Nucleic acids research
1362-4962: (2016)

PMID: 27899645

The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy.

Thienpont B, Aronsen JM, Robinson EL

The Journal of clinical investigation
1558-8238: (2016)

PMID: 27893464

Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms.

Hore TA, von Meyenn F, Ravichandran M

Proceedings of the National Academy of Sciences of the United States of America
1091-6490: (2016)

PMID: 27729528

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.

von Meyenn F, Berrens RV, Andrews S

Developmental cell
39 1878-1551:104-115 (2016)

PMID: 27728778

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.

Eckersley-Maslin MA, Svensson V, Krueger C

Cell reports
17 2211-1247:179-92 (2016)

PMID: 27681430

In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine.

Iurlaro M, McInroy GR, Burgess HE

Genome biology
17 1474-760X:141 (2016)

PMID: 27356509

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Clark SJ, Lee HJ, Smallwood SA

Genome biology
17 1474-760X:72 (2016)

PMID: 27091476