Life Sciences Research for Lifelong Health

Research

We are interested in understanding how chromatin-modifying proteins interact with signalling pathways and key transcription factors in order to coordinate cell fate decisions during development and stem cell differentiation.

For these experiments, we study pluripotent stem cells (mouse and human) in conditions that support either self-renewal or promote the initial stages of differentiation, in combination with genetic manipulation and modern genomic/epigenomic approaches.


Research Projects

Generation of the major cell lineages

Chromatin

Proteins