Life Sciences Research for Lifelong Health

Clara Novo

Clara obtained her Ph.D. in 2010 under the supervision of Nicola Royle (University of Leicester). The focus of her thesis was on the mechanisms that underlie MS32 minisatellite instability in telomeres. Clara was awarded Fellowships to study the replication and organisation of telomeres with Arturo Londoño-Vallejo (Institute Curie, Paris) followed by the investigation of epigenetic alterations of telomeres in cancer with Vincent Castronovo and Denis Mottet (Institute GIGA, Liege). Funded by the EpiGeneSys Network (www.epigenesys.eu), Clara joined the Babraham Institute in 2013 to study the three-dimensional organisation of the genome in stem cells and reprogramming.

Latest Publications

Derivation and Culture of Epiblast Stem Cell (EpiSC) Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)

PMID: 28049783

Derivation and Culture of Extra-Embryonic Endoderm Stem Cell Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093963 (2017)

PMID: 28049782

Crosstalk between pluripotency factors and higher-order chromatin organization.

Lopes Novo C, Rugg-Gunn PJ

Nucleus (Austin, Tex.)
1949-1042:0 (2016)

PMID: 27759487

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.

von Meyenn F, Berrens RV, Andrews S

Developmental cell
39 1878-1551:104-115 (2016)

PMID: 27728778

Chromatin organization in pluripotent cells: emerging approaches to study and disrupt function.

Lopes Novo C, Rugg-Gunn PJ

Briefings in functional genomics
2041-2657: (2015)

PMID: 26206085