Life Sciences Research for Lifelong Health
Lab 2016.jpg

Bhupinder Virk

I studied at University College London (UCL) for a B.Sc. in Genetics. It was then that my love for C. elegans and my interest in the field of ageing began - it intrigued me that something so tiny could potentially answer such big questions about ageing and health. After getting my Master’s degree at Imperial College London, I moved “oop north”, to Durham University for my PhD. I used the C. elegans: E. coli (host/microbe) model to look at interactions between host and gut bacteria – focussing on how particular metabolites might influence health and ageing.

After my PhD, I went to Shanghai Jiao Tong University to set up a fully functioning C. elegans facility, as part of a collaboration project. Five months of continuous tropical monsoons and power-cuts later, I was happy to come back to the UK, for a position developing training material in the Bioinformatics group at the Babraham Institute.

Bioinformatics is pretty cool, but I missed the worms! I’m excited to have joined the Casanueva lab as a postdoc, to investigate the mechanisms underlying the widespread rewiring of proteostasis networks during early phases of the ageing process. When I’m not “worming”, I enjoy movies, theatre, live music and fitness classes.

Latest Publications

Epigenetic inheritance of proteostasis and ageing.

Li C, Casanueva O

Essays in biochemistry
60 1744-1358:191-202 (2016)

PMID: 27744335

Fitness trade-offs and environmentally induced mutation buffering in isogenic C. elegans.

MO Casanueva, A Burga, B Lehner

Science (New York, N.Y.)
335 6064:82-5 (2012)

DOI: 10.1126/science.1213491

PMID: 22174126

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells.

SM Garcia, MO Casanueva, MC Silva

Genes & development
21 22:3006-16 (2007)

DOI: 10.1101/gad.1575307

PMID: 18006691

Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling.

MO Casanueva, EL Ferguson

Development (Cambridge, England)
131 9:1881-90 (2004)

DOI: 10.1242/dev.01076

PMID: 15105369

At least two receptors of asymmetric acetylcholinesterase are present at the synaptic basal lamina of Torpedo electric organ.

OI Casanueva, P Deprez, T García-Huidobro

Biochemical and biophysical research communications
250 2:312-7 (1998)

DOI: 10.1006/bbrc.1998.9303

PMID: 9753626