Molecular control of conventional and innate-like T cell development and functionMy long-term research interest is to characterize molecular mechanisms that regulate the development and function of T cells. Together with my laboratory I made important contributions to the transcriptional control of Cd8 gene expression and identified that the transcription factor MAZR is an important regulator of CD8 expression as well as of CD4/CD8 lineage development. Moreover, I am interested in elucidating the roles of histone deacetylases (HDACs) in T cells and e.g. we recently identified that CD4+ T cell lineage integrity is regulated by HDAC1 and HDAC2. I have also a long-standing interest in revealing the role of Tec family kinases in the regulation of immune responses. In ongoing studies my team addresses topics like: (1) Transcriptional control of CD4/CD8 cell fate choice; (2) Transcription factor networks regulating peripheral T cell function; (3) Maintenance of T cell lineage identity, integrity and function; (4) Characterization of signaling pathways modulating Th differentiation.
If you would like to attend this seminar, please use the "Contact us" link below to express interest and arrange site access.
|Starts||01:00 pm - 12/07/2016|
|Ends||02:00 pm - 12/07/2016|
|Contact||Dr Marc Veldhoen|
|Location||The Brian Heap Seminar Room|
|Speaker||Prof. Wilfried Ellmeier|
|Speaker Affiliation||Division of Immunibiology, Institute of Immunology, Medical University of Vienna, Austria|
15 June, 2016