Ageing Seminar: Mitochondria and the Cytoskeleton - regulators of life and death in the face of stress
The ability to connect environmental sensing to cell fate lies at the heart of a healthy cell population. Recent research suggest a central and conserved role for the actin cytoskeleton in such connections as it participates in both adaptive and cell death signalling. We have employed the model eukaryote S. cerevisiae to establish how corruption of the actin cytoskeleton, which commonly observed in ageing cells, triggers cells death. In this talk I will discuss how actin regulates cell death by reprogramming transcriptional networks and triggers reactive oxygen species (ROS) accumulation to accelerate cell ageing.
If you wish to meet with Dr Gourlay please contact Jon Houseley - firstname.lastname@example.org
|Starts||01:00 pm - 06/03/2014|
|Location||Brian Heap Room|
|Speaker||Dr Campbell Gourlay|
|Speaker Affiliation||University of Kent|
3 March, 2014